Cerebral Autoregulation in Subjects Adapted and Not Adapted to High Altitude

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Cerebral autoregulation in subjects adapted and not adapted to high altitude.

BACKGROUND AND PURPOSE Impaired cerebral autoregulation (CA) from high-altitude hypoxia may cause high-altitude cerebral edema in newcomers to a higher altitude. Furthermore, it is assumed that high-altitude natives have preserved CA. However, cerebral autoregulation has not been studied at altitude. METHODS We studied CA in 10 subjects at sea level and in 9 Sherpas and 10 newcomers at an alt...

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Antibody formation in rabbits adapted and nonadapted to high altitude.

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Endogenous Asymmetric Dimethylarginine Pathway in High Altitude Adapted Yaks

Hypoxia-induced and high altitude pulmonary hypertension are a major problem in the mountain areas of the world. The asymmetric methylarginines (ADMA) inhibit nitric oxide (NO) synthesis by competing with L-arginine, and high levels of plasma ADMA predict adverse outcomes in pulmonary hypertension. However, little is known about the regulation of the ADMA-NO pathway in animals adapted to high a...

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Milk at altitude: Human milk macronutrient composition in a high-altitude adapted population of Tibetans.

OBJECTIVE The physiological challenges of high altitude have led to population-specific patterns of adaptation. These include alterations to child growth and reproduction, including lactation. However, while breastfeeding has been investigated, nothing is known about milk composition in high altitude adapted populations. MATERIALS AND METHODS Here, we investigate milk macronutrient compositio...

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ژورنال

عنوان ژورنال: Stroke

سال: 2000

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.31.10.2314